with lipstick.

WOW! SPOT ON the money Frien. <

Thanks. I am learning FAST.

THESE PEOPLE ARE FUCKING SICK!

Thank you Sir for posting this.

I needed to read it.

Now I can expand my own research. <

Peace.

That is awful, but needs to be understood. Your post is very informative.

Ok. So in other words, all this "Liddle'" stuf that Trump is constantly mentioning is pointing to the fact that Schitt has the same 'syndrome' > [Diddling young kids] as Lewis Carrol had. They are Pedophiles. And Trump is calling them out HARD. I get it now.

I am going to get onto The LiDDle Kidz Foundation, as they obviously named their Pedophile organization after Lewis Carroll's child lover Alice et al, they are rubbing what they do in our faces. Child massage indeed! SICK AF!

NO MORE.

I SEE YOU NOW MOTHER FUCKERS.

'o-o' <

D5

Thank you President Trump for highlighting this. I understand now.

5:5

PAIN TIME. <

[LIDDLE' SYNDROME]

Other Names:

Pseudoaldosteronism; Liddle's syndrome

Categories:

Blood Diseases; Congenital and Genetic Diseases; Kidney and Urinary Diseases

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Summary

Liddle syndrome is a rare, inherited condition that is primarily characterized by severe high blood pressure (hypertension) that often develops at an early age. Although the condition may not be associated with signs and symptoms initially, untreated hypertension can eventually lead to heart disease or stroke. Affected people may also have low levels of potassium in the blood (hypokalemia) and metabolic alkalosis. Liddle syndrome is caused by mutations in either the SCNN1B or SCNN1G genes and is inherited in an autosomal dominant manner. Treatment may include a low sodium diet and potassium-sparing diuretics to reduce blood pressure and normalize potassium levels. Conventional anti-hypertensive therapies are not effective.[1][2]

Last updated: 11/15/2016

Symptoms

Liddle syndrome is primarily characterized by severe, early-onset hypertension (high blood pressure). Although the condition may not be associated with any signs and symptoms initially, untreated hypertension can eventually lead to heart disease and stroke. Affected people may also have hypokalemia (low blood potassium) and metabolic alkalosis. Symptoms of hypokalemia can include weakness, fatigue, muscle pain (myalgia), constipation or heart palpitations. In most cases, the condition becomes apparent at a young age but some affected people are not diagnosed until well into adulthood.[2][1]

Last updated: 11/15/2016

This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

Showing 14 of 14 |

Medical Terms Other Names

Learn More:

HPO ID

80%-99% of people have these symptoms

Arrhythmia

Abnormal heart rate

Heart rhythm disorders

Irregular heart beat

Irregular heartbeat

[ less ] 0011675

Constipation 0002019

Hypertension 0000822

Hypokalemia

Low blood potassium levels

0002900

30%-79% of people have these symptoms

Cerebral ischemia

Disruption of blood oxygen supply to brain

0002637

Fatigue

Tired

Tiredness

[ less ] 0012378

Muscle weakness

Muscular weakness

0001324

Nephropathy 0000112

Renal insufficiency

Renal failure

Renal failure in adulthood

[ less ] 0000083

Percent of people who have these symptoms is not available through HPO

Autosomal dominant inheritance 0000006

Decreased circulating aldosterone level

Low blood aldosterone level

0004319

Decreased circulating renin level 0003351

Hypokalemic alkalosis 0001949

Metabolic alkalosis 0200114

Showing 14 of 14 |

Do you have more information about symptoms of this disease? We want to hear from you.

Last updated: 9/1/2019

Do you have updated information on this disease? We want to hear from you.

Cause

Liddle syndrome is caused by changes (mutations) in the SCNN1B or SCNN1G gene. Each of theses genes provides instructions for making one piece of a protein complex called the epithelial sodium channel (ENaC). These channels are found on the surface of certain cells (epithelial cells) throughout the body, including the kidneys, lungs, and sweat glands. The ENaC channel transports sodium into cells.[3][4]

Mutations in the SCNN1B and SCNN1G genes affect an important region of the protein involved in signaling for its breakdown (degradation). As a result of the mutations, the protein is not tagged for degradation when it is no longer needed, and more ENaC channels remain at the cell's surface. The increase in channels at the cell surface abnormally increases the reabsorption of sodium, which leads to hypertension. Because removal of potassium from the blood is linked with reabsorption of sodium, excess sodium reabsorption leads to hypokalemia.[1]

Last updated: 11/15/2016

Inheritance

Liddle syndrome is inherited in an autosomal dominant manner.[1] This means that to be affected, a person only needs a change (mutation) in one copy of the responsible gene in each cell. In some cases, an affected person inherits the mutation from an affected parent. Other cases may result from new (de novo) mutations in the gene. These cases occur in people with no history of the disorder in their family. A person with Liddle syndrome has a 50% chance with each pregnancy of passing along the altered gene to his or her child.

Last updated: 11/15/2016

Diagnosis

A diagnosis of Liddle syndrome is often suspected based the presence of early-onset hypertension (high blood pressure), especially in people with a family history of the condition. Additional testing can then be ordered to confirm the diagnosis. This may include:[5][2]

FOUND IT. Adam Schiff and Moby at Little Pine Restaurant.

Liddles disease is a disease treated by low salt diets and/or kidney replacement. Moby regularly feeds Adam Schiff vegan meals at his restaurant Little Pine. Vegan is notoriously low sodium. (http://archive.is/waWB7)

I don't even need to start digging on little pine to know we will find symbolism of a familiar sort there...

"It depends on what the definition of "is" is...."

No wonder they think we are sheep.

lol

Look it up? Really? You rude motherfucker!

Also used to indicate missing letters such as "it's" = "it has" or "it is".

"it is" becomes "it's

Liddle’d? As in that three year old child was just Liddle’d by Adam Schiff?

Hi Fonzi