Hydroxychloroquine, Ivermectin, doxycyline and many other drugs are
1.) proven to inhibit SARS CoV 2 in vitro in infected human cells, i.e. they shut down the infection because the virus can’t reproduce.
2.) proven to work in patients when given early (before patients progress to severe form)
3.)Can be taken prophylactically in low doses long term. HCQ and doxycyline are used long term for all kinds of conditions. They will prevent most cases and reduce the severity of infection. They will also lessen “asymptomatic” spread.
When people push you around on the mask shit or the social distancing push back with these facts. Demand antivirals prophylactically and otc for covid.
The good shit in quinine will kill and prevent all sorts of baddies (NOT COVID because it is bullshit). Commercial tonic water apparently is largely diluted so best to get the real deal (wild quinine, cinchona bark, etc.)
I am fairly confident about the content of name brands like schweppes and canada dry being around 65mg of quinine base a liter, if they haven’t changed their recipe in the last year— cinchona is undoubtedly in high demand, they do not manufacture it synthetically. Other generics might have only 50 mg /liter or less. Legally 83mg/liter is allowed but it doesn’t seem to ever have that much. Quinine fluoresces under UV black light in the dark so you can compare brands— you may be able to tell a difference of +-20% concentration difference.
Unfortunately you can’t boil off the water content without destroying quinine.
Typical doses of quinine sulfate for acute malaria are around 1200 mg a day to as much as 1800 mg a day of quinine sulfate (600mg for people with kidney disease). Quinine sulfate is 83% quinine, so I figure an equivalent dose of quinine base is about 1000mg. That would be a safety limit for me, maybe much less for people with cardiac, diabetic and kidney issues.
1000 mg is like 16 liters of tonic a day.
But I suspect a dose of around 300 or 350mg (5 or 6 liters) would make a big difference in the viral load if used at onset of symptoms.
Another solution is tonic syrup concentrate. Top Hat makes a sugar and sugar-free version. I like the sugar free one for obvious reasons. The claim is that it has 5x the quinine of regular tonic (5x 50mg? 5x 83 mg? Who knows? But it clearly has more than the regular tonic water) Its $20 a quart on amazon (less in bulk) but I have not bought any yet. You might want to approximate the concentration of quinine with a UV light unless you own a fluorometer. Lol. This would be one way to get around drinking all that tonic, but I am much less confident about the quinine content of that product, which makes me nervous about recommending it.
I would be even less confident about doses derived from extracting quinine out of cinchona bark. But again you might be able to eyeball it with a UV light and comparing it to tonic water in various concentrations. I think the top hat thing is probably easier though.
Realize that people with kidney or heart issues would be particularly vulnerable to overdose issues if you fucked up. Also a significant number of people have an allergy to quinine.
Hope I didn’t go overboard on the information dump. Ive researched quinine a little bit over the last few months.
4 to 8 cups of tonic water (~60 to 120mg quinine base) will probably prevent most covid infections and lessen the severity of the ones it doesn’t. That’s an educated guess. A liter a day should make a significant difference. Brand names have higher concentrations.
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Helena73 ago
Hydroxychloroquine, Ivermectin, doxycyline and many other drugs are
1.) proven to inhibit SARS CoV 2 in vitro in infected human cells, i.e. they shut down the infection because the virus can’t reproduce.
2.) proven to work in patients when given early (before patients progress to severe form)
3.)Can be taken prophylactically in low doses long term. HCQ and doxycyline are used long term for all kinds of conditions. They will prevent most cases and reduce the severity of infection. They will also lessen “asymptomatic” spread.
When people push you around on the mask shit or the social distancing push back with these facts. Demand antivirals prophylactically and otc for covid.
Bigz_Sarducci ago
So a glass of tonic water a day keeps the covid away?
beefartist ago
The good shit in quinine will kill and prevent all sorts of baddies (NOT COVID because it is bullshit). Commercial tonic water apparently is largely diluted so best to get the real deal (wild quinine, cinchona bark, etc.)
Bigz_Sarducci ago
The ppm to drinking tonic water and getting the medical amount is alot. But it does have its purpose.
Helena73 ago
I am fairly confident about the content of name brands like schweppes and canada dry being around 65mg of quinine base a liter, if they haven’t changed their recipe in the last year— cinchona is undoubtedly in high demand, they do not manufacture it synthetically. Other generics might have only 50 mg /liter or less. Legally 83mg/liter is allowed but it doesn’t seem to ever have that much. Quinine fluoresces under UV black light in the dark so you can compare brands— you may be able to tell a difference of +-20% concentration difference.
Unfortunately you can’t boil off the water content without destroying quinine.
Typical doses of quinine sulfate for acute malaria are around 1200 mg a day to as much as 1800 mg a day of quinine sulfate (600mg for people with kidney disease). Quinine sulfate is 83% quinine, so I figure an equivalent dose of quinine base is about 1000mg. That would be a safety limit for me, maybe much less for people with cardiac, diabetic and kidney issues.
1000 mg is like 16 liters of tonic a day.
But I suspect a dose of around 300 or 350mg (5 or 6 liters) would make a big difference in the viral load if used at onset of symptoms.
Another solution is tonic syrup concentrate. Top Hat makes a sugar and sugar-free version. I like the sugar free one for obvious reasons. The claim is that it has 5x the quinine of regular tonic (5x 50mg? 5x 83 mg? Who knows? But it clearly has more than the regular tonic water) Its $20 a quart on amazon (less in bulk) but I have not bought any yet. You might want to approximate the concentration of quinine with a UV light unless you own a fluorometer. Lol. This would be one way to get around drinking all that tonic, but I am much less confident about the quinine content of that product, which makes me nervous about recommending it.
I would be even less confident about doses derived from extracting quinine out of cinchona bark. But again you might be able to eyeball it with a UV light and comparing it to tonic water in various concentrations. I think the top hat thing is probably easier though.
Realize that people with kidney or heart issues would be particularly vulnerable to overdose issues if you fucked up. Also a significant number of people have an allergy to quinine.
Hope I didn’t go overboard on the information dump. Ive researched quinine a little bit over the last few months.
beefartist ago
Some is WAY better than none but for the cost of the stuff I would assume you can make your own for less and have a higher dosage
Bigz_Sarducci ago
True
Helena73 ago
4 to 8 cups of tonic water (~60 to 120mg quinine base) will probably prevent most covid infections and lessen the severity of the ones it doesn’t. That’s an educated guess. A liter a day should make a significant difference. Brand names have higher concentrations.