It usually occurs in males rather than females and is commonly seen in Northern Europeans. It tends to run in families. Alcoholism, diabetes, prior hand trauma, and manual labor with vibration exposure are just some of the risk factors.
Dupuytren contracture is most commonly observed in persons of Northern European descent and affects 4-6% of Caucasians worldwide. [2] Many individuals have bilateral disease (45%); in unilateral cases, the right side is more often affected. [3] The ring finger is most commonly involved, followed by the fifth digit and then the middle finger. The index finger and the thumb are typically spared.
Although the cause of Dupuytren disease is unknown, a family history is often present. Males are three times as likely to develop disease and are more likely to have higher disease severity. [4, 5] Male predominance may be related to expression of androgen receptors in Dupuytren fascia.
Other potential risk factors include manual labor with vibration exposure, prior hand trauma, alcoholism, smoking, diabetes mellitus, hyperlipidemia, Peyronie disease, and complex regional pain syndrome. [7] Rheumatoid arthritis seems to protect against the development of Dupuytren disease.
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MyNameIsLuka ago
What's with "fellow hand sufferer"??
Celticgirlonamission ago
Dupuytrens it causes hands to contract fingers are pulled towards palm of hand this usually happens to skinny white males that drink heavily
equineluvr ago
It usually occurs in males rather than females and is commonly seen in Northern Europeans. It tends to run in families. Alcoholism, diabetes, prior hand trauma, and manual labor with vibration exposure are just some of the risk factors.
Dupuytren contracture is most commonly observed in persons of Northern European descent and affects 4-6% of Caucasians worldwide. [2] Many individuals have bilateral disease (45%); in unilateral cases, the right side is more often affected. [3] The ring finger is most commonly involved, followed by the fifth digit and then the middle finger. The index finger and the thumb are typically spared.
Although the cause of Dupuytren disease is unknown, a family history is often present. Males are three times as likely to develop disease and are more likely to have higher disease severity. [4, 5] Male predominance may be related to expression of androgen receptors in Dupuytren fascia.
Other potential risk factors include manual labor with vibration exposure, prior hand trauma, alcoholism, smoking, diabetes mellitus, hyperlipidemia, Peyronie disease, and complex regional pain syndrome. [7] Rheumatoid arthritis seems to protect against the development of Dupuytren disease.
http://emedicine.medscape.com/article/329414-overview