More than 20 mutations in the PAX2 gene have been found to cause renal coloboma syndrome. Most mutations are specific to each affected family; however, one mutation has been found in multiple affected individuals. This mutation inserts one DNA building block (nucleotide) into the PAX2 gene (written as 619insG). Most mutations occur in the region of the protein that attaches to DNA, impairing its function as a transcription factor. A lack of functional PAX2 protein disrupts the formation of certain tissues (particularly the kidneys and eyes) during embryonic development, causing the signs and symptoms of renal coloboma syndrome.
Gee, I wonder how I got confused. You are way too paranoid.
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Tanngrisnir ago
James Alefantis doesn't have Pax6 caused Coloboma, I don't think. Caris James does.
DMTco2Melatonin ago
It's pax6, not pax2. Congenital mutations within pax6 transcription resulting in "snake in the eye".
I know this is bait NSA. I'm not stupid.
Tanngrisnir ago
Damn, man. I get a detail wrong and you think I am NSA?
DMTco2Melatonin ago
Yes, I do.
Tanngrisnir ago
More than 20 mutations in the PAX2 gene have been found to cause renal coloboma syndrome. Most mutations are specific to each affected family; however, one mutation has been found in multiple affected individuals. This mutation inserts one DNA building block (nucleotide) into the PAX2 gene (written as 619insG). Most mutations occur in the region of the protein that attaches to DNA, impairing its function as a transcription factor. A lack of functional PAX2 protein disrupts the formation of certain tissues (particularly the kidneys and eyes) during embryonic development, causing the signs and symptoms of renal coloboma syndrome.
Gee, I wonder how I got confused. You are way too paranoid.
https://ghr.nlm.nih.gov/gene/PAX2
DMTco2Melatonin ago
I'm not paranoid, I am a product of MKUltra and highly psychic.
It's Pax6 you are looking for as then people will make the discovery of the vikings. Thanks for playing NSA, bye.