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MercurysBall2 ago

Effects of Mescaline, LSD-25, and Adrenochrome on Depth Electrograms in Man, 1956 by BERT E. SCHWARZ, M.D.; CARL W. SEM-JACOBSEN, M.D.; MAGNUS C. PETERSEN, M.D. - https://jamanetwork.com/journals/archneurpsyc/article-abstract/652212

From the Rochester State Hospital.

Abstract

In a recent report concerning the reversibility by chlorpromazine of psychoses induced by means of mescaline and d-lysergic acid diethylamide (LSD-25), careful attention was given to the clinical and electroencephalographic changes.1 Although the clinical changes of this reversal effect were immediate and striking, the conventional electroencephalographic changes were minimal, and it was difficult to assess them. It was noted in another recent study that mescaline and LSD-25 failed to activate temporal-lobe epilepsy either clinically or electroencephalographically.2

Because of these factors, it was hoped that depth electrographic studies might be fruitful in elucidating the effects of these drugs. It was hoped also that study by means of depth electrography of the effects of adrenochrome might elucidate its reported actions of inducing a psychosis without insight in volunteers3 and increasing the paroxysmal discharges in the electroencephalograms of epileptics.4 Scalp electroencephalography and depth electrography were undertaken as specific

MercurysBall2 ago

Simons Foundation https://en.wikipedia.org/wiki/Simons_Foundation

As of December 2018, the Simons Foundation is listed as a White House BRAIN Initiative Alliance Member.[11] The Simons Collaboration on the Global Brain (SCGB) is working to understand the internal processes underlying cognition

Simons Foundation Autism Research Initiative https://en.wikipedia.org/wiki/Simons_Foundation_Autism_Research_Initiative

The Simons Foundation Autism Research Initiative, or SFARI for short, is a research program established in 2005 by the Simons Foundation, which focuses on all aspects of autism research. Its director is Louis Reichardt.. Marilyn Simons, the Simons Foundation's president, is on the board of directors, as are David Eisenbud and James H. Simons

One specific type of research they specialize in is mouse models of autism, which they are trying to make more available in cooperation with the Jackson Laboratory.

In 2016, SFARI launched Simons Foundation Powering Autism Research for Knowledge (SPARK), an online research initiative designed to become the largest autism study ever undertaken in the United States. For researchers, SPARK provides a large, well-characterized cohort of genetic, medical and behavioral data, and will result in cost-savings for researchers by reducing start-up costs for individual studies.

Flatiron Institute https://www.simonsfoundation.org/flatiron/

The mission of the Flatiron Institute is to advance scientific research through computational methods, including data analysis, theory, modeling and simulation

The institute, an internal research division of the Simons Foundation, is a community of scientists who are working to use modern computational tools to advance our understanding of science, both through the analysis of large, rich datasets and through the simulations of physical process.

Director David Spergel: Using microwave background observations from the Wilkinson Microwave Anisotropy Probe (WMAP) and the Atacama Cosmology Telescope, I have measured the age, shape and composition of the universe. Our observations have played a significant role in establishing the standard model of cosmology. I am one of the leaders of the Simons Observatory, which will include a planned millimeter-wave telescope that will allow us to take the next step in studying the microwave sky and probing the history of the universe.

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